Synthesis of a Variety of 4,5-Functionalized Imidazol-2-Ylidenes from a Single 4,5-Unsubstituted Imidazol-2-Ylidene. J. Am. Chem. Soc. 2010, 132, 7264-7265.
Mendoza Espinosa, Daniel
2010
Mendoza-Espinosa, D.; Donnadieu, B.; Bertrand, G. Synthesis of a Variety of 4,5-Functionalized Imidazol-2-Ylidenes from a Single 4,5-Unsubstituted Imidazol-2-Ylidene. J. Am. Chem. Soc. 2010, 132, 7264-7265.
Abstract
Using the nucleophilicity of NHCs and aNHCs, as well as the leaving group ability of the former, the carbon?carbon double bond of imidazol-2-ylidenes can be readily mono- and difunctionalized. These results provide also a new light on the formation of abnormal carbene adducts from classical unsaturated NHCs.
Artículos relacionados
Total Syntheses of Five Indole Alkaloids from the Marine Bryozoan Flustra foliacea
Regioselective Synthesis of 3-Indolyl(alkoxy)acetates
Conformational studies on indole alkaloids from Flustra foliacea by NMR and molecular modeling
The absoluteconfiguration of cuauhtemone and related compounds
Synthesis of Bromoindole Alkaloids from Laurencia brongniartii
Absolute configuration determination of 2-(2-oxo-3-indolyl)acetamide derivatives
Role of lipid peroxidation in biliary obstruction in the rat