Producción Científica Profesorado

The absoluteconfiguration of cuauhtemone and related compounds

Suárez Castillo, Oscar Rodolfo


The absolute configuration of cuauhtemone and related compounds. Torres-Valencia J. M., Quintero-Mogica D. L., León G. I., Suárez-Castillo O. R., Villagómez-Ibarra J. R., Maldonado E., Cerda-García-Rojas C. M., Joseph-Nathan P. DOI:


The absoluteconfiguration of cuauhtemone, a eudesmane-type sesquiterpene isolated from Pluchea species (Asteraceae), has been revised from 1 to 2 by chemical correlation with (R)-(+)-2-methyl-1,2-butanediol 3 through the naturally occurring 2,3-epoxy-2-methylbutanoate derivative 4. The relative stereochemistry of 4 was confirmed by X-ray diffraction analysis. The obtained data are also useful for reconsideration of the absoluteconfigurations of a relevant group of natural products, which were elucidated according to the stereochemistry of cuauhtemone.

Producto de Investigación

Artículos relacionados

Cleavage of alkoxycarbonyl protecting groups from carbamates by t-BuNH2

Reactivity of TpMe2Ir(C2H4)(DMAD) with carboxylic acids. A DFT study on geometrical isomers and stru...

Cascade [1,3]-Sigmatropic Rearrangements of Ketene O,O-Acetals: Kinetic and DFT Level Mechanistic St...

Preparation of 3-hydroxyoxindoles with dimethyldioxirane and their use for the synthesis of natural ...

Role of lipid peroxidation in biliary obstruction in the rat

Total Syntheses of Five Indole Alkaloids from the Marine Bryozoan Flustra foliacea

Stereochemical assignment of naturally occurring 2,3-epoxy-2-methylbutanoate esters

Absolute configuration determination of 2-(2-oxo-3-indolyl)acetamide derivatives

Synthesis of Acetamido(indol-3-yl)propanol Derivatives

One-potsynthesis of conformationallyrestrictedspirooxindoles