Phenylboronic acid catalyzed-cyanide promoted, one-pot synthesis of 2-(2-hydroxyphenyl)benzoxazole derivatives
Rojas Lima, Susana
2011
Heraclio López-Ruiz, Horacio Briseño-Ortega, Susana Rojas-Lima, Rosa Santilllán, Norberto Farfán. Phenylboronic acid catalyzed-cyanide promoted, one-pot synthesis of 2-(2-hydroxyphenyl)benzoxazole derivatives . Tetrahedron Letters 2011, 52, 4308-4312. DOI: http://dx.doi.org/10.1016/j.tetlet.2011.06.039
Abstract
A novel, one-pot, phenylboronic acid catalyzed, cyanide promoted synthesis of 2-(2-hydroxyphenyl)benzoxazoles from salicylaldehydes and o-aminophenols is described. The synthesis is characterized by mild conditions, short reaction times, and simple workup of crystalline, high purity products.
Artículos relacionados
Facile synthesis of 1,3,6-oxadiazepines from 2,2?-(1,2-ethanediyldiimino)bisphenols
Preparation of N-aryl-substituted spiro-?-lactams via Staudinger cycloaddition