Producción Científica Profesorado

Physicochemical characterization of an arabinoxylan-rich fraction from brewers' spent grain and its application as a release matrix for caffeine



Alvarez Romero, Giaan Arturo

2019

Perez-Flores, JG., Contreras-Lopez, E., Castaneda-Ovando, A. , Perez-Moreno, F., Aguilar-Arteaga, K., Alvarez-Romero, GA., Tellez-Jurado, A., Physicochemical characterization of an arabinoxylan-rich fraction from brewers' spent grain and its application as a release matrix for caffeine, Food Research International, 2019,116, 1020-1030. doi.org/10.1016/j.foodres.2018.09.041


Abstract


The brewers' spent grain is a by-product generated during brewery process and is a potential source for arabinoxylans (AX) extraction. In the present work, the extraction and characterization of an arabinoxylan-rich fraction from brewers' spent grain (BSG-AX) were performed, and BSG-AX was evaluated as release matrix for caffeine. The BSG-AX showed an AX content of 72% (w/w), a ferulic acid content of 3.52??g/mg BSG-AX, an Ara/Xyl ratio of 0.89, an intrinsic viscosity of 41.18?mL?g?1, and a molecular weight of 43.80?kDa. The studied BSG-AX showed a good antioxidant capacity compared with other polysaccharide gums and was estimated by DPPH (114.41??M Trolox equivalent/g BSG-AX) and FRAP (49.01??mol Fe2+/g BSG-AX) assays. The partial specific volume (0.63?cm3?g?1), loss on drying (10.68%), swelling (10.87%), solubility (80.93%) and electrostatic interactions (by zeta potential, ?3.44 to ?9.17?mV) were determined and used to evaluate the application of the BSG-AX as release matrix. A film containing the BSG-AX, glycerol (as plasticizer) and caffeine (target drug) was prepared as release matrix. Glycerol promoted an increase in the extensibility and the surface smoothness of the BSG-AX-caffeine film. The drug was released (?98%) in about 7?h. These results are promising to concern the design and use of BSG-AX based biofilms for the controlled release of bioactive compounds.



Producto de Investigación




Artículos relacionados

Metal content evaluation and its effect on the stability of anthocyanins

Simultaneous determination of tetracyclines in poultry muscle by capillary zone electrophoresis

Determination of glucose by flow injection analysis with amperometric detection at Fe(III)-(tris(3,5...

Determination of non-steroidal anti-inflammatory drugs in wastewaters by magnetic matrix solid phase...

Sequential Injection Spectrophotometric Determination of Diclofenac in Urine and Pharmaceutical Form...

Potentiometric quantification of saccharin by using a selective membrane formed by pyrrole electropo...

Chemical studies of anthocyanins: A review

Nucleation and Growth Kinetics of Electrodeposited Sulfate-Doped Polypyrrole: Determination of the D...

Chemical studies of anthocyanins: A review

Potentiometric Behavior of Diverse Polypyrrolesulphate Films Electro Synthesized on Graphite Epoxy ...