Producción Científica Profesorado

Determination of antibiotics in feedstuff samples by microemulsion electrokinetic chromatography using fullerene as additive



Ibarra Ortega, Israel S.

2018

Nieto, N.K., Rodriguez, J.A., Ibarra, I.S., Cruz-Borbolla, J., Vasquez-Perez, J.M., Electrophoresis, (2018), 39, 2228-2235. DOI: 10.1002/elps.201800094


Abstract


A microemulsion electrokinetic chromatography method was developed for the simultaneous detection and quantification of ciprofloxacin, norfloxacin, sulfamethoxazole, tetracycline, and oxytetracycline in feedstuff samples. The BGE composition was optimized by applying a Taguchi parameter design and consisted of phosphate 30 mmol/L, Tween?80 0.01 mmol/L, and fullerene 3 ?mol/L, and adjusted to pH 8.0; the addition of surfactant and fullerene modifies the mobility of the analytes improving their resolution. Theoretical studies showed ??? and van der Waals interactions between antibiotic molecules and fullerene used as a pseudostationary phase. Under optimal conditions, limits of detection ranged from 0.7 to 1.5 ?g/g; the analytes were separated in less than 6 min. The methodology proposed is useful for controlling and monitoring antibiotic residues in feedstuff samples.



Producto de Investigación




Artículos relacionados

High-performance liquid magneto-chromatography

Mercury Ions Removal from Aqueous Solution Using an Activated Composite Membrane

Sequential Injection Spectrophotometric Determination of Diclofenac in Urine and Pharmaceutical Form...

Metal content evaluation and its effect on the stability of anthocyanins

Synthesis, characterization, and crystal structures of n-alkyldiorganodithiophosphates RS2P(OC6H4)2

Characterization of Main Anthocyanins Extracted from Pericarp Blue Corn by MALDI-ToF MS

cis-Palladium(II) complexes of derivatives of di-(2-pyridyl)methane: Study of the influence of the b...

Presence and antimicrobial resistance of Escherichia coli isolated from foodstuffs in Hidalgo State ...

Construction and Evaluation of a Gold Tubular Electrode for Flow Analysis: Application to Speciation...

Determination of tetracyclines in milk samples by magnetic solid phase extraction flow injection ana...