Producción Científica Profesorado

Determination of tetracyclines in milk samples by magnetic solid phase extraction flow injection analysis



Rodríguez Ávila, José Antonio

2010

Rodriguez, J.A, Espinosa, J., Aguilar-Arteaga, K., Ibarra, I.S., Miranda, J.M. Determination of tetracyclines in milk samples by magnetic solid phase extraction flow injection analysis, Microchimica Acta, 2010, Vol. 171, p. 407413, ISSN 0026-3672


Abstract


A method is presented for magnetic solid phase extraction (MSPE) of tetracyclines in milk samples. The method involves the extraction and clean-up by silica based magnetic support dispersion on non-pretreated milk samples, followed by the magnetic isolation and desorption of the analytes by acidified methanol. The tetracyclines eluted from the magnetic support were determined simultaneously by flow injection analysis with spectrophotometric detection. Under optimal conditions, the linear range of the calibration curve ranges from 0.03 to 0.60 mg L?1, with a limit of detection of 10 ?g L?1. Recoveries were determined for milk spiked at levels from 0.15 to 0.60 mg L?1. Average recoveries ranged from 91.0 to 97.0%, with a precision of <5.0% in all cases. The method was validated by comparing the results with those obtained by MSPE-HPLC and SPE-HPLC. No significant differences were observed (p?



Producto de Investigación




Artículos relacionados

Determination of primary amino acids in wines by high performance liquid magneto-chromatography

Potentiometric behavior of graphite-epoxy electrochemical transducers towards anions, cations and pH...

Characterization of Main Anthocyanins Extracted from Pericarp Blue Corn by MALDI-ToF MS

Nucleation and Growth Kinetics of Electrodeposited Sulfate-Doped Polypyrrole: Determination of the D...

Development of a Chloride Ion-Selective Solid State Sensor Based on Doped Polypyrrole-Graphite-Epoxy...

Sequential Injection Spectrophotometric Determination of Diclofenac in Urine and Pharmaceutical Form...

Sequential Injection Spectrophotometric Determination of Diclofenac in Urine and Pharmaceutical Form...

Potentiometric quantification of saccharin by using a selective membrane formed by pyrrole electropo...

Development of a novel composite sensor based on doped pyrrole selective to nitrate ions

Chemical studies of anthocyanins: A review