Cleavage of alkoxycarbonyl protecting groups from carbamates by t-BuNH2
Suárez Castillo, Oscar Rodolfo
2007
Cleavage of alkoxycarbonyl protecting groups from carbamates by t-BuNH2. Oscar R. Suárez-Castillo, Luis Alberto Montiel-Ortega, Myriam Meléndez-Rodríguez, Maricruz Sánchez-Zavala. DOI: http://dx.doi.org/10.1016/j.tetlet.2006.11.024
Abstract
An efficient, simple protocol for the selective cleavage of a variety of N-alkoxycarbonyl protecting groups by t-BuNH2/MeOH is described. The scope of the procedure was explored for a series of indole, aniline and pyrrolidine carbamate derivatives containing other potentially reactive functional groups affording a clean cleavage of the carbamate group.
Artículos relacionados
Conformational studies on indole alkaloids from Flustra foliacea by NMR and molecular modeling
Synthesis of Bromoindole Alkaloids from Laurencia brongniartii
Configuration, stereodynamics and crystal structure of 3-substituted-2-oxofuro[2,3-b]indoles
Role of lipid peroxidation in biliary obstruction in the rat
Aromatic Bromination versus Oxidation of Indolylmalonates by Bromine
Synthesis of 6-bromo-2-arylindoles using 2-iodobenzoic acid as precursor