Cleavage of alkoxycarbonyl protecting groups from carbamates by t-BuNH2
Suárez Castillo, Oscar Rodolfo
2007
Cleavage of alkoxycarbonyl protecting groups from carbamates by t-BuNH2. Oscar R. Suárez-Castillo, Luis Alberto Montiel-Ortega, Myriam Meléndez-Rodríguez, Maricruz Sánchez-Zavala. DOI: http://dx.doi.org/10.1016/j.tetlet.2006.11.024
Abstract
An efficient, simple protocol for the selective cleavage of a variety of N-alkoxycarbonyl protecting groups by t-BuNH2/MeOH is described. The scope of the procedure was explored for a series of indole, aniline and pyrrolidine carbamate derivatives containing other potentially reactive functional groups affording a clean cleavage of the carbamate group.
Artículos relacionados
Total Syntheses of Five Indole Alkaloids from the Marine Bryozoan Flustra foliacea
Role of lipid peroxidation in biliary obstruction in the rat
Conformational studies on indole alkaloids from Flustra foliacea by NMR and molecular modeling
Synthesis of Bromoindole Alkaloids from Laurencia brongniartii
Unimolecular rearrangements of ketene-O,O-acetals and fragmentations occurring in the gas phase
Synthesis of Acetamido(indol-3-yl)propanol Derivatives
The absoluteconfiguration of cuauhtemone and related compounds