Producción Científica Profesorado

Determination of non-steroidal anti-inflammatory drugs in wastewaters by magnetic matrix solid phase dispersionHPLC



Rodríguez Ávila, José Antonio

2010

Aguilar-Arteaga, K., Rodriguez, J.A., Miranda, J.M., Medina, J., Barrado, E. Determination of non-steroidal anti-inflammatory drugs in wastewaters by magnetic matrix solid phase dispersionHPLC, Talanta, 2010, Vol. 80, p. 11521157, ISSN 0039-9140


Abstract


A series of supports functionalized with different alkyl chains and covered with magnetite were synthesized, characterized and applied in the sample pre-concentration of four non-steroidal anti-inflammatory drugs (acetaminophen, naproxen, diclofenac and ibuprofen) contained in wastewater samples. The general methodology involved magnetic solid phase dispersion followed by the analysis by high-performance liquid chromatography with ultraviolet detection. The magnetic supports were initially dispersed in the samples with the aid of Triton X-100, then supports were magnetically isolated and the analytes were eluted with methanol. Finally the extract was injected into the HPLC system. The highest recovery percentage (>90%) was obtained with the support containing octyl chains (C8) at pH 3. The lowest limits of detection achieved ranged within 12 ?g L?1 with repeatability (expressed as RSD) below 5% in all cases. The method was applied in the analysis of wastewater samples.



Producto de Investigación




Artículos relacionados

Development of a novel composite sensor based on doped pyrrole selective to nitrate ions

Determination of tetracyclines in milk samples by magnetic solid phase extraction flow injection ana...

Potentiometric quantification of saccharin by using a selective membrane formed by pyrrole electropo...

Multicommutated Anodic Stripping Voltammetry at Tubular Bismuth Film Electrode for Lead Determinatio...

Prevalence and Antimicrobial Resistance Patterns of Salmonella from Different Raw Foods in Mexico

Sequential Injection Spectrophotometric Determination of Diclofenac in Urine and Pharmaceutical Form...

Renewable stationary phase liquid magnetochromatography: determining aspartame and its hydrolysis pr...

Design and Construction of Solid State Ag/AgCl Reference Electrodes Through Electrochemical Depositi...

High-performance liquid magneto-chromatography

Determination of primary amino acids in wines by high performance liquid magneto-chromatography