Producción Científica Profesorado

Magnetic Solid-Phase Extraction Based on Poly 4-Vinyl Pyridine for HPLC-FLD Analysis of Naproxen in Urine Samples



Ibarra Ortega, Israel S.

2020

Escamilla-Lara, K.A., Heredia, A.C., Peña-Alvarez, A., Ibarra, I.S., Barrado, E., Rodriguez, J.A. Magnetic solid-phase extraction based on poly 4-vinyl pyridine for HPLC-FLD analysis of naproxen in urine samples. Molecules, 2020,25, 25122924. DOI: 10.3390/molecules25122924


Abstract


A magnetic solid phase extraction technique followed by liquid chromatography with a fluorescence detector for naproxen analysis in human urine samples was developed. The method includes the extraction of naproxen with a magnetic solid synthetized with magnetite and poly 4-vinylpriridine, followed by the magnetic separation of the solid phase and desorption of the analyte with methanol. Under optimal conditions, the linear range of the calibration curve was 0.05?0.60 ?g L?1, with a limit of detection of 0.02 ?g L?1. In all cases values of repeatability were lower than 5.0% with recoveries of 99.4 1.3%. Precision and accuracy values are adequate for naproxen (Npx) analysis in urine samples.



Producto de Investigación




Artículos relacionados

Development of a novel composite sensor based on doped pyrrole selective to nitrate ions

Chemical studies of anthocyanins: A review

Potentiometric quantification of saccharin by using a selective membrane formed by pyrrole electropo...

Determination of oxytetracycline in milk samples by polymer inclusion membrane separation coupled to...

Chemical studies of anthocyanins: A review

Estudio de las Interacciones Ácido Húmico-Metales Pesados y Determinación de sus Constantes de Estab...

Magnetic solids in analytical chemistry: A review

Potentiometric quantification of saccharin by using a selective membrane formed by pyrrole electropo...

Facilitated transport of Hg(II) through novel activated composite membranes

cis-Palladium(II) complexes of derivatives of di-(2-pyridyl)methane: Study of the influence of the b...