Producción Científica Profesorado

Synthesis of a Variety of 4,5-Functionalized Imidazol-2-Ylidenes from a Single 4,5-Unsubstituted Imidazol-2-Ylidene. J. Am. Chem. Soc. 2010, 132, 7264-7265.



Mendoza Espinosa, Daniel

2010

Mendoza-Espinosa, D.; Donnadieu, B.; Bertrand, G. Synthesis of a Variety of 4,5-Functionalized Imidazol-2-Ylidenes from a Single 4,5-Unsubstituted Imidazol-2-Ylidene. J. Am. Chem. Soc. 2010, 132, 7264-7265.


Abstract


Using the nucleophilicity of NHCs and aNHCs, as well as the leaving group ability of the former, the carbon?carbon double bond of imidazol-2-ylidenes can be readily mono- and difunctionalized. These results provide also a new light on the formation of abnormal carbene adducts from classical unsaturated NHCs.






Artículos relacionados

Absolute configuration determination of 2-(2-oxo-3-indolyl)acetamide derivatives

First Total Synthesis of ()-Flustraminol B

Cleavage of alkoxycarbonyl protecting groups from carbamates by t-BuNH2

Regioselective Synthesis of 3-Indolyl(alkoxy)acetates

Total Syntheses of Five Indole Alkaloids from the Marine Bryozoan Flustra foliacea

13C NMR and crystallographic evidence of push-pull effects in furoindolic ?-enamino esters

Cascade [1,3]-Sigmatropic Rearrangements of Ketene O,O-Acetals: Kinetic and DFT Level Mechanistic St...

Unimolecular rearrangements of ketene-O,O-acetals and fragmentations occurring in the gas phase

Conformational studies on indole alkaloids from Flustra foliacea by NMR and molecular modeling

Synthesis of Bromoindole Alkaloids from Laurencia brongniartii