Producción Científica Profesorado

Synthesis of a Variety of 4,5-Functionalized Imidazol-2-Ylidenes from a Single 4,5-Unsubstituted Imidazol-2-Ylidene. J. Am. Chem. Soc. 2010, 132, 7264-7265.



Mendoza Espinosa, Daniel

2010

Mendoza-Espinosa, D.; Donnadieu, B.; Bertrand, G. Synthesis of a Variety of 4,5-Functionalized Imidazol-2-Ylidenes from a Single 4,5-Unsubstituted Imidazol-2-Ylidene. J. Am. Chem. Soc. 2010, 132, 7264-7265.


Abstract


Using the nucleophilicity of NHCs and aNHCs, as well as the leaving group ability of the former, the carbon?carbon double bond of imidazol-2-ylidenes can be readily mono- and difunctionalized. These results provide also a new light on the formation of abnormal carbene adducts from classical unsaturated NHCs.






Artículos relacionados

13C NMR and crystallographic evidence of push-pull effects in furoindolic ?-enamino esters

Synthesis of Indolylindolines Mediated by tert-BuNH2

Unimolecular rearrangements of ketene-O,O-acetals and fragmentations occurring in the gas phase

Synthesis of Acetamido(indol-3-yl)propanol Derivatives

Synthesis of Bromoindole Alkaloids from Laurencia brongniartii

Synthesis of ?4:?2-Exocyclic-Diene Iridium(I) Complexes Derived from 1,3-Oxazolidin-2-ones and Their...

First Total Synthesis of ()-Flustraminol B

Synthesis of 6-bromo-2-arylindoles using 2-iodobenzoic acid as precursor

Firsttotalsyntheses of dihydroflustramine C and flustramine E, alkaloids from the marine bryozoan Fl...

Preparation of 3-hydroxyoxindoles with dimethyldioxirane and their use for the synthesis of natural ...