Synthesis of a Variety of 4,5-Functionalized Imidazol-2-Ylidenes from a Single 4,5-Unsubstituted Imidazol-2-Ylidene. J. Am. Chem. Soc. 2010, 132, 7264-7265.
Mendoza Espinosa, Daniel
2010
Mendoza-Espinosa, D.; Donnadieu, B.; Bertrand, G. Synthesis of a Variety of 4,5-Functionalized Imidazol-2-Ylidenes from a Single 4,5-Unsubstituted Imidazol-2-Ylidene. J. Am. Chem. Soc. 2010, 132, 7264-7265.
Abstract
Using the nucleophilicity of NHCs and aNHCs, as well as the leaving group ability of the former, the carbon?carbon double bond of imidazol-2-ylidenes can be readily mono- and difunctionalized. These results provide also a new light on the formation of abnormal carbene adducts from classical unsaturated NHCs.
Artículos relacionados
Regioselective Synthesis of 3-Indolyl(alkoxy)acetates
Synthesis of Acetamido(indol-3-yl)propanol Derivatives
Trapping enols of esters and lactones with diazomethane
Role of lipid peroxidation in biliary obstruction in the rat
Aromatic Bromination versus Oxidation of Indolylmalonates by Bromine
Stereochemical assignment of naturally occurring 2,3-epoxy-2-methylbutanoate esters
First Total Synthesis of ()-Flustraminol B
Synthesis of Bromoindole Alkaloids from Laurencia brongniartii