Producción Científica Profesorado

Optimization of a Differential Pulse Voltammetric Methodology for the Quantification of Diclofenac Using Paste Electrodes and Carbon Nanotubes



Alvarez Romero, Giaan Arturo

2017

M. Franco Guzmán, G. A. Álvarez Romero, L. H. Mendoza Huizar, C. A. Galán Vidal, G. Roa Morales, M. T. Ramírez Silva, M. G. Montes de Oca Yemh, ECS Trans., 2017, 76(1), 9-18.doi: 10.1149/07601.0009ecst


Abstract


In this work we present the development of an optimizedmethodology based on differential pulse voltammetry fordiclofenac quantification, using electrochemically activated carbonpaste electrodes and multi-walled nanotubes carbon pasteelectrodes. Under the optimized experimental conditions,diclofenac presented linear response over the range of 10-10 to 10-4M for both electrodes. The lower detection limits found were 0.001and 0.29 ?M for the paste electrodes with and without nanotubesrespectively. The effect of common interferences on diclofenaccurrent response was investigated. Finally the proposedmethodology was validated comparing the results obtainedmeasuring the concentration of diclofenac in pharmaceuticalsamples with those obtained with the reference methodology.



Producto de Investigación




Artículos relacionados

Determination of primary amino acids in wines by high performance liquid magneto-chromatography

Magnetic solid phase extraction based on phenyl silica adsorbent for the determination of tetracycli...

Development of a novel nitrate-selective composite sensor based on doped polypyrrole

Multicommutated Anodic Stripping Voltammetry at Tubular Bismuth Film Electrode for Lead Determinatio...

Validation of a tubular bismuth film amperometric detector: Determination of diclofenac sodium by mu...

Development of a Chloride Ion-Selective Solid State Sensor Based on Doped Polypyrrole-Graphite-Epoxy...

Metal content evaluation and its effect on the stability of anthocyanins

Potentiometric quantification of saccharin by using a selective membrane formed by pyrrole electropo...

Characterization of Main Anthocyanins Extracted from Pericarp Blue Corn by MALDI-ToF MS

Determination of non-steroidal anti-inflammatory drugs in wastewaters by magnetic matrix solid phase...