Absolute confirmation assignment of oxindole derivatives by vibrational circular dichroism exciton coupling
Sánchez Zavala, Maricruz
2016
Claudia I. Bautista-Hernández, Reyna E. Cordero-Rivera, Erick A. Zúñiga-Estrada, Nayely Trejo-Carbajal, Myriam Meléndez-Rodríguez, Óscra R. Suárez-Castillo, Maricruz Sánchez-Zavala, Martha S. Moraler-Ríos y Pedro Joseph-Nathan. ?Absolute confirmation assignment of oxindole derivatives by vibrational circular dichroism exciton coupling? Tetrahedron: Asymmetry, 27, 623-638, (2016).
Abstract
A convenient and reliable approach for the absolute configuration assignment of oxindole derivatives 2a?m by vibrational circular dichroism (VCD) measurements and evaluation of the VCD bisignated couplet resulting from the interaction of the C2 and C9 carbonyl groups is presented. The absolute configuration assignments were further tested by 1H NMR measurements and by X-ray diffraction analysis.
Artículos relacionados
Mechanisticstudies of the photochemicalrearrangement of 1-oxolongipin-2-ene derivatives
Photochemical rearrangements of highly functionalized longipinene derivatives
DFT and NMR parameterized conformation of valeranone
Absolute configuration determination of 2-(2-oxo-3-indolyl)acetamide derivatives
Transesterifications mediated by t-BuNH2
First Total Synthesis of ()-Flustraminol B
Synthesis of Bromoindole Alkaloids from Laurencia brongniartii