Producción Científica Profesorado

Copper(II) complexes supported by click generated mixed NN, NO, and NS 1,2,3-triazole based ligands and their catalytic activity in azide?alkyne cycloaddition



Alvarez Hernandez, Alejandro

2014

Daniel Mendoza-Espinosa, Alejandro Álvarez-Hernández, Guillermo Enrique Negrón-Silva, Oscar R. Suárez-Castillo, Deyanira Ángeles-Beltrán and Rosa Santillán. Copper(II) complexes supported by click generated mixed NN, NO, and NS 1,2,3-triazole based ligands and their catalytic activity in azide?alkyne cycloaddition. Dalton Trans. 2014, 43, 7069-7077.


Abstract


The preparation and characterization of four new copper(II) complexes supported by click generated mixed NN, NO, and NS 1,2,3-triazoles are reported. The four complexes display a 1 : 2 copper/ligand ratio and give monomeric units in the solid state. Crystal structures demonstrate that depending on the flexibility of the ligand NX (X = O, N, S) pendant arm, the coordination environment around the metal center can feature square planar or octahedral geometries. All four complexes are catalytically active at room temperature in a copper-catalyzed alkyne?azide cycloaddition (CuAAC) reaction using sodium ascorbate as a reducing agent and water?ethanol as a solvent mixture. Complex 8 supported by the NS ligand displayed the best catalytic performance of the series allowing for the easy and high yielding preparation of a variety of mono-, bis- and tris-1,2,3-triazoles under low catalyst loadings.



Producto de Investigación




Artículos relacionados

r-Alkylation of (S)-Asparagine with Self-Regeneration of the Stereogenic Center: Enantioselective Sy...

The Structural Chemistry of N-Monolithium Borazines

Facile synthesis of 1,3,6-oxadiazepines from 2,2?-(1,2-ethanediyldiimino)bisphenols

Effect of TiO2Al2O3 SolGel Supports on the Superficial Ni and Mo Species in Oxidized and Sulfided Ni...

An efficient potassium cyanide-promoted synthesis of 2-arylbenzoxazoles from [4.3.0]boron heterobicy...

Stereoselective addition of allylmagnesium chloride to the CN bond of [4.3.0] boron heterobicycles

Furocoumarins of three species of the genus Dorstenia

X-ray crystallographic study of neutral boron chelates with ?-diketones and tropolone

Diastereomeric C-glycosyloxanthrones from picramnia antidesma

ChemInform Abstract: Facile Preparation of [4.4]Metacyclophane- and [5.5]Paracyclophane-Type Macrocy...