2012
Suárez-Castillo, O. R., Bautista-Hernández, C. I., Sánchez-Zavala, M., Meléndez-Rodríguez, M. Sierra-Zenteno, A., Morales-Ríos, M. S., & Joseph-Nathan, Pedro. (2012). Microwave-assisted synthesis of 3,1-benzoxazin-2-ones from 3-hydroxyoxindoles?. Heterocycles 85, 2147-2171.
Abstract
A general protocol for the synthesis of 3,1-benzoxazin-2-ones 18 from 3-hydroxyoxindoles 16 in a two steps sequence through phenylsuccinates or phenylpropionates 17 is described. Best reaction conditions for ring opening of 16 to succinates or propionates17 were achieved using alcohol/silica gel, while cyclization of 17 to benzoxazinones 18 was easily done with HCl/alcohol. It was also found that 17 and 18 can be transesterified using HCl/alcohol. Most transformations were carried out by traditional heating and by microwave (MW) irradiation to accelerate reaction rates.
DFT and NMR parameterized conformation of valeranone
Photochemical rearrangements of highly functionalized longipinene derivatives
Absolute configuration determination of 2-(2-oxo-3-indolyl)acetamide derivatives
Synthesis of Bromoindole Alkaloids from Laurencia brongniartii
Mechanisticstudies of the photochemicalrearrangement of 1-oxolongipin-2-ene derivatives
First Total Synthesis of ()-Flustraminol B
Regioselective Synthesis of 3-Indolyl(alkoxy)acetates
Cleavage of alkoxycarbonylprotectinggroups from carbamates by t-BuNH2