Synthesis and structural studies of new N-(p-toluenesulfonyl)amino acid o-phenolamides
Tlahuextl Romero, Angela Margarita
2004
Liliana Aguilar-Castro, Margarita Tlahuextl, Antonio R. Tapia-Benavides*, José Guadalupe Alvarado-Rodríguez, Structural Studies by NMR and X-ray Crystallography of N-(p-toluenesulfonyl)-Amino Acids, Structural Chemistry, 15(3), 215-221 (2004). DOI: 10.1002/hc.10135
Abstract
N-(p-Toluenesulfonyl)glycine o-phenolamide (3a) and the analogous derivatives of d,l-alanine (3b), l-valine (3c), l-leucine (3d), and l-phenylalanine (3e) were synthesized in yields >80% by condensation of N-(p-toluenesulfonyl)amino acyl chlorides with o-aminophenol. The structure and conformation of these amides were established by NMR spectroscopy and X-ray crystallography.
Artículos relacionados
Structural studies of spiroarsoranes derived from 2-aminophenols
Three-center intramolecular hydrogen bonding in oxamide derivatives. NMR and X-ray diffraction study
Synthesis of Zn compounds derived from 1H-benzimidazol-2-ylmethanamine
Do Spiroarsoranes Exhibit Polytopal Equilibrium in Solution?