Producción Científica Profesorado

Diastereoselective alkylation of chiral glycinate derivatives containing the a-phenylethyl group.

Tapia Benavides, Antonio Rafael


Rodríguez-Garnica Cristina, López-Ruiz Heraclio,* Rojas-Lima Susana, Álvarez - Hernández Alejandro, Tapia-Benavides Rafael, García-López María Concepción. Diastereoselective alkylation of chiral glycinate derivatives containing the ?-phenylethyl group. Journal of the Mexican Chemical Society, 55(3), 148-153. (2011)


Novel chiral glycinate derivatives (S)-6 and (S)-7 containing the a-phenylethyl group, were prepared and studied as potentialprecursors of enantiopure a-substituted-a-amino acids. In particular, the alkylation of enolate (S)-7-Li showed substantial (78:22 dr)stereoinduction by the N-(1-phenylethyl)benzamide chiral auxiliary.Addition of DMPU showed no appreciable effect upon the diastereoselectivity

Producto de Investigación

Artículos relacionados

Do Spiroarsoranes Exhibit Polytopal Equilibrium in Solution?

New 3,3?[2,2?-oxy-bis-(oxazaborolidine)]-ethylenes. Structural studies by NMR, X-ray, and quantum ch...

trans-Bis[2-(aminomethyl)-1H-benzimidazole-2N2,N3]aquacopper(II) dichloride dihydrate

1,4,7,8-Triazaborabicyclooctanesfirst examples of new boron heterocycles [1,2]

Synthesis and structural studies of new N-(p-toluenesulfonyl)amino acid o-phenolamides

Three-center intramolecular hydrogen bonding in oxamide derivatives. NMR and X-ray diffraction study

Hydrogen bond studies in substituted N-(2-hydroxyphenyl)--2-[(4-methylbenzenesulfonyl)amino]acetamid...

Crystal structure, ferromagnetostructural behavior and evidence of cooperative JahnTeller interactio...

Speciation of the new ligand di-isopropyliminodiacetoamide with Cu(II) using computational processin...

Structural and spectroscopic characterisation of tris(2-benzimidazolylmethyl)amine coordination comp...