Facile synthesis of 1,3,6-oxadiazepines from 2,2?-(1,2-ethanediyldiimino)bisphenols
Rojas Lima, Susana
2001
Ma. Eugenia Ochoa Becerra, Susana Rojas-Lima, Herbert Höpfl, Patricia Rodríguez, Dolores Castillo, Rosa Luisa Santillán Baca and José Norberto Farfán García. "Facile synthesis of 1,3,6-oxadiazepines from 2,2'-(1,2-ethanediyldiimino)bisfenols. Tetrahedron, 57, 55-64 (2001). DOI: http://dx.doi.org/10.1016/S0040-4020(00)00984-4
Abstract
A useful sequence of reactions for the syntheses of a variety of heterocyclic systems including an oxadiazepine ring is described. The key step involves the condensation of substituted 2,2?-(1,2-ethanediyldiimino)bisphenols with ethanedial to provide stereoselectively the 6a,7a-trans-6,6a,7a,8,15,16-hexahydro[1,4]benzoxazine[4?,3?:6,7][1,3,6]oxadiazepino[2,3-c][1,4]-benzoxazine-6,8-diol framework, as established by X-ray diffraction analyses.
Artículos relacionados
Diastereoselective alkylation of chiral glycinate derivatives containing the ?-phenylethyl group.
Aroylthioureas: new organic ionophores for heavy-metal ion selective electrodes
Study of the reactivity of squarylferrocenes. Addition of amines and aminoesters
Et3B, an Efficient Mediator for Xanthate Transfer Based Radical Processes
Synthesis and Structures of some Lithium and Sodium (Aminoalcoholato)hydrido Aluminates