Daniel Omar González-Ábrego, Gloria Sánchez-Cabrera, Francisco J. Zuno-Cruz, Jose A. Rodriguez, José G. Alvarado-Rodríguez, Noemí Andrade-López, Jorge A. López, Crispin Cristobal, Gerardo González-García. Cu(I) and Pd(II) complexes containing ?-thioketoiminate ligands and their evaluation as potential redox mediators for electrochemical biosensors. Inorganica Chimica Acta2021, 514, 120000. https://doi.org/10.1016/j.ica.2020.120000
The synthesis of the [Cu(SacNacDipp)(PPh3)] (1) and [Pd(SacNacDipp)Cl(PPh3)] (2) complexes was achieved from deprotonation of the 4-(2,6-diisopropylphenylamino)-3-penten-2-thione ligand. Both compounds were characterized in solution by IR and NMR studies and their molecular structures were determined by single crystal X-ray diffraction studies. The electrochemical properties of both complexes were studied to evaluate their capability to detect hydrogen peroxide; as a result of its electrochemical behavior, 1 was used as redox mediator for glucose determination biosensor using the enzyme glucose oxidase (GOx).