2018
Regulating Noncovalent Interactions in amino-amide-Copper Complexes. Víctor Lechuga-Islas, Hugo Tlahuext, Martha P. Falcón-León, Félix Sánchez-De Jesús, Rosa E. Moo-Puc, Juan B. Chale-Dzul, Antonio R. Tapia-Benavides*, Margarita Tlahuextl*. Eur. J. Inorg. Chem, 2018, 1419-1426, doi: 10.1002/ejic.201701332
Abstract
The relevance of intermolecular noncovalent ClCu interactions in the magnetic and biological behavior of copper complexes derived from amino amides is studied. Crystallography studies show that these complexes tend to stack, favoring noncovalent interactions (hydrogen bonding and CuCl). However, the presence of substituents at the C10 and C13 positions regulates the supramolecular structures in 2. Thus, magnetic studies at 93, 293, and 353 K demonstrate that magnetic exchange is favored only by Cu?ClCu interactions. Moreover, biological studies show that only those copper complexes with ferromagnetic behavior present cytotoxic activity. Natural bond orbital (NBO) and quantum theory of atoms in molecules (QTAIM) computations are used to corroborate the presence of the noncovalent interactions.
ChemInform Abstract: Syntheses of N-Substituted 2,5-Piperazindiones.
trans-Bis[2-(aminomethyl)-1H-benzimidazole-2N2,N3]aquacopper(II) dichloride dihydrate
Synthesis and structural studies of new N-(p-toluenesulfonyl)amino acid o-phenolamides
Synthesis of Zn compounds derived from 1H-benzimidazol-2-ylmethanamine