Producción Científica Profesorado

Absolute configuration assignment of oxindole derivatives by vibrational circular dichroism exciton coupling.



Suárez Castillo, Oscar Rodolfo

2016

Claudia I. Bautista-Hernández, Reyna E. Cordero-Rivera, Erick A. Zúñiga-Estrada, Nayely Trejo-Carbajal, Myriam Meléndez-Rodríguez, Oscar R. Suárez-Castillo, Maricruz Sánchez-Zavala, Martha S. Morales-Ríos, Pedro Joseph-Nathan. Absolute configuration assignment of oxindole derivatives by vibrational circular dichroism exciton coupling. Tetrahedron: Asymmetry, 2016, 27, 623-638. http://dx.doi.org/10.1016/j.tetasy.2016.06.004


Abstract


A convenient and reliable approach for the absolute configuration assignment of oxindole derivatives 2a?m by vibrational circular dichroism (VCD) measurements and evaluation of the VCD bisignated couplet resulting from the interaction of the C2 and C9 carbonyl groups is presented. The absolute configuration assignments were further tested by 1H NMR measurements and by X-ray diffraction analysis.



Producto de Investigación




Artículos relacionados

13C NMR and crystallographic evidence of push-pull effects in furoindolic ?-enamino esters

Configuration, stereodynamics and crystal structure of 3-substituted-2-oxofuro[2,3-b]indoles

Synthesis of 6-bromo-2-arylindoles using 2-iodobenzoic acid as precursor

Total Syntheses of Five Indole Alkaloids from the Marine Bryozoan Flustra foliacea

Synthesis of Indolylindolines Mediated by tert-BuNH2

The absoluteconfiguration of cuauhtemone and related compounds

Preparation of 3-hydroxyoxindoles with dimethyldioxirane and their use for the synthesis of natural ...

Unimolecular rearrangements of ketene-O,O-acetals and fragmentations occurring in the gas phase

Role of lipid peroxidation in biliary obstruction in the rat

One-potsynthesis of conformationallyrestrictedspirooxindoles