2016
Raúl Balderrama-Martínez-Sotomayor, Mariana Flores-Jarillo, Alejandro Alvarez-Hernandez. Preparation of symmetrical C2-C2-linked bis- and tris-6-bromoindoles by Sonogashira couplings and 5-endo-dig cyclization induced by nBu4NF. ARKIVOC, 2016 ,(iii), 36-47http://quod.lib.umich.edu/a/ark/5550190.p009.319/1
Abstract
Preparation of symmetrical C2-C2 linked bis-6-bromoindoles and one tris-6-bromoindole containing ether spacers is described. Double regioselective Sonogashira coupling at the C-I bond of benzyl (5-bromo-2-iodophenyl)carbamate with dialkynes allowed preparation of the corresponding bis-benzyl(2-alkynyl-5-bromo)carbamates. Tetrabutylammonium fluoride (TBAF) promoted 5-endo-dig cyclization was successful with substrates derived from alkyldialkynes but failed with substrates derived from aryldialkynes as base catalysis was not sufficient to promote nucleophilic attack on these electron rich alkynes.
X-ray crystallographic study of neutral boron chelates with ?-diketones and tropolone
A flexible access to highly functionalised boronates
Study of the reactivity of squarylferrocenes. Addition of amines and aminoesters
Et3B, an Efficient Mediator for Xanthate Transfer Based Radical Processes
Preparation of N-aryl-substituted spiro-?-lactams via Staudinger cycloaddition
Diastereoselective Synthesis of Spiro-?-lactams via Staudinger Reactio