Producción Científica Profesorado

Evaluation of the use of solvent impregnated resins in the analysis of salbutamol in human urine followed by capillary electrophoresis.



Galan Vidal, Carlos Andres

2016

Irma Pérez-Silva, Ma. Teresa Ramírez-Silva, Carlos A. Galán-Vidal, Giaan A. Álvarez-Romero, José A. Rodríguez, Ma. Elena Páez-Hernández. Evaluation of the use of solvent impregnated resins in the analysis of salbutamol in human urine followed by capillary electrophoresis.Reactive and Functional Polymers, 2016, 105, 89-94


Abstract


In this work, a method for sorption and concentration of salbutamol in urine combined to capillary electrophoresis with UV detection was performed. The procedure is based on the sorption of salbutamol on solvent-impregnated resins that is prepared by an impregnation technique using Aliquat 336 as extractant and XAD-4 resin as the base polymer. Batch studies showed an efficient sorption/desorption results when the salbutamol solution contains NaOH 0.05 mol L? 1 and the eluent is 0.5 mol L? 1 NaCl. Linearity was obtained in the range of 1000?10,000 ng mL? 1 of salbutamol. The limit of quantification was 999 ng mL? 1. The solvent-impregnated resin was used for 10 cycles without a significant loss of the salbutamol quantification capacity. The method was applied to analyze salbutamol in urine samples at levels useful for international health organizations. Although most reports of solvent impregnated resins are related to the extraction of metal ions and only a few organic compounds, the proposed methodology demonstrate that solvent impregnated resins allows the isolation and concentration of salbutamol from complex samples such as urine. Since no SB is recovered using resin without Aliquat 336, this work shows an advantage of SIR over simple adsorption processes.



Producto de Investigación




Artículos relacionados

Synthesis of Zn compounds derived from 1H-benzimidazol-2-ylmethanamine

Estudio de las Interacciones Ácido Húmico-Metales Pesados y Determinación de sus Constantes de Estab...

Nucleation and growth of cobalt onto different substrates: Part II. The upd-opd transition onto a go...

Análisis del Comportamiento Presión-Temperatura en la Transición Isotrópico-Nemático del p-Azoxianis...

Analysis of the experimental pressuretemperature behavior in the isotropicnematic phase transition f...

Efecto de la composición del soporte sobre las estructuras superficiales de óxidos de níquel y molib...

A Voltammetric Study Of The Underpotential Deposition Of Cobalt Onto A Glassy Carbon Electrode

Underpotential deposition of cobalt onto polycrystalline platinum

Revisión de variables de diseño y condiciones de operación en la electrocoagulación

A theoretical quantum study on the distribution of electrophilic and nucleophilic active sites on Ag...