Phenylboronic Acid/CuSO4 as an Efficient Catalyst for the Synthesis of 1,4-Disubstituted-1,2,3-Triazoles from Terminal Acetylenes and Alkyl Azides
Rojas Lima, Susana
2015
José Emilio de la Cerda-Pedro, Susana Rojas-Lima, Rosa Santillan and Heraclio López-Ruiz*, Phenylboronic Acid/CuSO4 as an Efficient Catalyst for the Synthesis of 1,4-Disubstituted-1,2,3-Triazoles from Terminal Acetylenes and Alkyl Azides, J. Mex. Chem. Soc. 2015, 59(2), 130-136
Abstract
The synthesis of 1,4-disubstituted-1,2,3-triazoles from alkylazides and terminal alkynes at room temperature and under microwaveheating was attained using Cu(I), generated in-situ fromcopper(II) sulfate and phenylboronic acid, as catalyst. Twelve newtriazoles were obtained in moderate to good yields (53-98%), and theproducts were obtained by crystallization from the mixture reactionwithout further purification
Artículos relacionados
Synthesis and Structures of some Lithium and Sodium (Aminoalcoholato)hydrido Aluminates
Ylidaddukte der Penteltrichloride
Et3, and efficient Mediator for Xanthate Transfer Based Radical Processes.
Diastereoselective alkylation of chiral glycinate derivatives containing the ?-phenylethyl group.
Diastereoselective Synthesis of Spiro-?-lactams via Staudinger Reaction
Diastereomeric C-glycosyloxanthrones from picramnia antidesma
Study of the reactivity of squarylferrocenes. Addition of amines and aminoesters