Pharmacokineticpharmacodynamic modelling of the analgesic effects of lumiracoxib, a selective inhibitor of cyclooxygenase-2, in ratsbph
Ortiz Ramírez, Mario Isidoro
2010
Vásquez-Bahena DA, Salazar-Morales UE, Ortiz MI, Castañeda-Hernández G, Trocóniz IF.Pharmacokinetic-pharmacodynamic modelling of the analgesic effects of lumiracoxib, a selective inhibitor of cyclooxygenase-2, in rats.Br J Pharmacol. 2010;159(1):176-87.ISSN 1476 5381
Abstract
This study establishes a pharmacokinetic/pharmacodynamic (PK/PD) model to describe the time course and in vivo mechanisms of action of the antinociceptive effects of lumiracoxib, evaluated by the thermal hyperalgesia test in rats.
Artículos relacionados
Primary dysmenorrhea among Mexican university students: prevalence, impact and treatment
ACEMETACIN ANTINOCICEPTIVE MECHANISM IS NOT RELATED TO NO OR K+ CHANNEL PATHWAYS
Antihyperalgesia Induced by Heliopsis longipes Extract
Antihyperalgesia Induced by Heliopsis longipes Extract
Effect of dietary selenium deficiency on the in vitro fertilizing ability of mice spermatozoa