2012
Morales-Rios, MS; Rivera-Becerril, E; Lopez-Camacho, PY ; Perez-Rojas, NA ; Suarez-Castillo, OR, Preparation of O-Methyl Substituted 2-Oxofuro- and 2-Oxopyrrolidinoindolines by Reductive Lactonization of Oxindol-3-ylacetic Acids, NATURAL PRODUCT COMMUNICATIONS. Año: 2012 Volume: 7 Issue: 11 Pages: 1445-1451.ISSN: 1934-578X
Abstract
A practical procedure for the preparation of O-methyl substituted 3a,8-dialkyl-2-oxofuroindolines is described. Reductive lactonization of the corresponding oxindol-3-ylacetic acids provides a route for the formation of this class of compounds. Further transformation of 2-oxofuroindolines into 2-oxopyrrolidinoindolines, and then to pyrrolidinoindolines demonstrates their versatility as key intermediates in natural products synthesis. The results of single-crystal X-ray crystallographic analyses are given for five of the studied compounds.
Regioselective Synthesis of 3-Indolyl(alkoxy)acetates
The absoluteconfiguration of cuauhtemone and related compounds
Role of lipid peroxidation in biliary obstruction in the rat
Trapping enols of esters and lactones with diazomethane
Conformational studies on indole alkaloids from Flustra foliacea by NMR and molecular modeling
Aromatic Bromination versus Oxidation of Indolylmalonates by Bromine
13C NMR and crystallographic evidence of push-pull effects in furoindolic ?-enamino esters
Configuration, stereodynamics and crystal structure of 3-substituted-2-oxofuro[2,3-b]indoles