Producción Científica Profesorado

Diastereoselective alkylation of chiral glycinate derivatives containing the a-phenylethyl group.



Tapia Benavides, Antonio Rafael

2011

Rodríguez-Garnica Cristina, López-Ruiz Heraclio,* Rojas-Lima Susana, Álvarez - Hernández Alejandro, Tapia-Benavides Rafael, García-López María Concepción. Diastereoselective alkylation of chiral glycinate derivatives containing the ?-phenylethyl group. Journal of the Mexican Chemical Society, 55(3), 148-153. (2011)


Abstract


Novel chiral glycinate derivatives (S)-6 and (S)-7 containing the a-phenylethyl group, were prepared and studied as potentialprecursors of enantiopure a-substituted-a-amino acids. In particular, the alkylation of enolate (S)-7-Li showed substantial (78:22 dr)stereoinduction by the N-(1-phenylethyl)benzamide chiral auxiliary.Addition of DMPU showed no appreciable effect upon the diastereoselectivity



Producto de Investigación




Artículos relacionados

Addition reactions of protonic reagents to optically active 2-phenyl-1,3,2-oxazaborolines

Speciation of the new ligand di-isopropyliminodiacetoamide with Cu(II) using computational processin...

ChemInform Abstract: Syntheses of N-Substituted 2,5-Piperazindiones.

Do Spiroarsoranes Exhibit Polytopal Equilibrium in Solution?

New 3,3?[2,2?-oxy-bis-(oxazaborolidine)]-ethylenes. Structural studies by NMR, X-ray, and quantum ch...

Hydrogen bond studies in substituted N-(2-hydroxyphenyl)--2-[(4-methylbenzenesulfonyl)amino]acetamid...

Synthesis and structural studies of N-(p-toluenesulfonyl)-amino acid 3,5-di-tert-butyl-2-phenolamide...

Diastereoselective alkylation of chiral glycinate derivatives containing the a-phenylethyl group.

Synthesis and structural studies of new N-(p-toluenesulfonyl)amino acid o-phenolamides

Synthesis and structural studies of new N-(p-toluenesulfonyl)amino acid o-phenolamides