Diastereoselective alkylation of chiral glycinate derivatives containing the a-phenylethyl group.
Tapia Benavides, Antonio Rafael
2011
Rodríguez-Garnica Cristina, López-Ruiz Heraclio,* Rojas-Lima Susana, Álvarez - Hernández Alejandro, Tapia-Benavides Rafael, García-López María Concepción. Diastereoselective alkylation of chiral glycinate derivatives containing the ?-phenylethyl group. Journal of the Mexican Chemical Society, 55(3), 148-153. (2011)
Abstract
Novel chiral glycinate derivatives (S)-6 and (S)-7 containing the a-phenylethyl group, were prepared and studied as potentialprecursors of enantiopure a-substituted-a-amino acids. In particular, the alkylation of enolate (S)-7-Li showed substantial (78:22 dr)stereoinduction by the N-(1-phenylethyl)benzamide chiral auxiliary.Addition of DMPU showed no appreciable effect upon the diastereoselectivity
Artículos relacionados
SYNTHESIS OF NOVEL DINUCLEAR COMPLEXES OF Fe(O) DERIVED FROM 1,2-DICARBONYLIC MONOHYDRAZONES
SYNTHESES, NMR STUDY AND STEREOCHEMISTRY OF NEW P-H TRICYCLOPHOSPHORANES
Synthesis and structural studies of new N-(p-toluenesulfonyl)amino acid o-phenolamides
ChemInform Abstract: Syntheses of N-Substituted 2,5-Piperazindiones.
Synthesis of Zn compounds derived from 1H-benzimidazol-2-ylmethanamine
Structural studies of spiroarsoranes derived from 2-aminophenols